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Linus Jönsson, Anders WimoRon HandelsGunilla JohanssonMercè BoadaSebastiaan EngelborghsLutz FrölichFrank JessenPatrick Gavin KehoeMilica KrambergerAlexandre de MendonςaPierre Jean OussetNikolaos ScarmeasPieter Jelle VisserGunhild WaldemarBengt Winblad, PMID: 37251789, PMCID: PMC10220264, DOI: 10.1016/j.lanepe.2023.100657.

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Boada M, Rodrigo A, Jessen F, Wimblad B, Kramberger MG, Visser PJ, Simó R, Rodríguez-Gomez O, Ciudin A, Georges J, Dumas A, Maguire P, Krivec D, Wimo A,
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Sannemann L, Müller T, Waterink L, Zwan M, Wimo A, Stomrud E, Pinó S, Arrufat J, Rodríguez-Gomez O, Benaque A, Bon J, Ferreira D, Johansson G, Dron A, Dumas A, Georges J, Kramberger MG, Visser PJ, Winblad B, Campo L, Boada M, Jessen F; MOPEAD consortium. General practitioners’ attitude toward early and
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Ingala S, De Boer C, Masselink LA, Vergari I, Lorenzini L, Blennow K, Chételat G, Di Perri C, Ewers M, van der Flier WM, Fox NC, Gispert JD, Haller S, Molinuevo JL, Muniz-Terrera G, Mutsaerts HJ, Ritchie CW, Ritchie K, Schmidt M, Schwarz AJ, Vermunt L, Waldman AD, Wardlaw J, Wink AM, Wolz R, Wottschel V, cheltens P, Visser PJ, Barkhof F; EPAD consortium. Application of the ATN classification scheme in a population without dementia: Findings from the EPAD cohort. Alzheimers Dement. 2021 Jul;17(7):1189-1204. doi: 10.1002/alz.12292. Epub 2021 Apr 3. PMID: 33811742; PMCID: PMC8359976

 

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Rodrigo A, Trigueros P, Jamilis L, Alegret M, Rodríguez O, Tárraga L, González-Pérez A, Kramberger M, Winblad B, Visser PJ, Jessen F, Campo L, Boada M; MOPEAD consortium. Identification of undiagnosed dementia cases using a web- based pre-screening tool: The MOPEAD project. Alzheimers Dement. 2021
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Altomare D, Molinuevo JL, Ritchie C, Ribaldi F, Carrera E, Dubois B, Jessen F, McWhirter L, Scheltens P, van der Flier WM, Vellas B, Démonet JF, Frisoni GB; European Task Force for Brain Health Services. Brain Health Services: organization, structure, and challenges for implementation. A user manual for Brain Health Services-part 1 of 6. Alzheimers Res Ther. 2021 Oct 11;13(1):168. doi: 10.1186/s13195-021-00827-2. PMID: 34635163; PMCID: PMC8507194

 

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Lopes Alves I, Collij LE, Altomare D, Frisoni GB, Saint-Aubert L, Payoux P, Kivipelto M, Jessen F, Drzezga A, Leeuwis A, Wink AM, Visser PJ, van Berckel
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Chincarini A, Peira E, Morbelli S, Pardini M, Bauckneht M, Arbizu J, Castelo-Branco M, Büsing KA, de Mendonça A, Didic M, Dottorini M, Engelborghs S, Ferrarese C, Frisoni GB, Garibotto V, Guedj E, Hausner L, Hugon J, Verhaeghe J, Mecocci P, Musarra M, Queneau M, Riverol M, Santana I, Guerra UP, Nobili F. Semi-quantification and grading of amyloid PET: A project of the European Alzheimer’s Disease Consortium (EADC). Neuroimage Clin. 2019;23:101846. doi: 10.1016/j.nicl.2019.101846. Epub 2019 May 4. PMID: 31077984; PMCID: PMC6514268.

 

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Zandifar A, Fonov VS, Pruessner JC, Collins DL; Alzheimer’s Disease Neuroimaging Initiative. The EADC-ADNI harmonized protocol for hippocampal segmentation: A validation study. Neuroimage. 2018 Nov 1;181:142-148. doi:10.1016/j.neuroimage.2018.06.077. Epub 2018 Jun 30. PMID: 29966720.

 

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Wolf D, Bocchetta M, Preboske GM, Boccardi M, Grothe MJ; Alzheimer’s Disease Neuroimaging Initiative. Reference standard space hippocampus labels according to the European Alzheimer’s Disease Consortium-Alzheimer’s Disease Neuroimaging Initiative harmonized protocol: Utility in automated volumetry. Alzheimers Dement. 2017 Aug;13(8):893-902. doi: 10.1016/j.jalz.2017.01.009. Epub 2017 Feb 24.PMID: 28238738.

 

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Gallivanone F, Della Rosa PA, Perani D, Gilardi MC, Castiglioni I; EADC-PET Consortium. The impact of different 18FDG PET healthy subject scans for comparison with single patient in SPM analysis. Q J Nucl Med Mol Imaging. 2017 Mar;61(1):115-132. doi: 10.23736/S1824-4785.16.02749-7. Epub 2014 Dec 5. PMID: 25479418.

 

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Frisoni GB, Jack CR. HarP: the EADC-ADNI Harmonized Protocol for manual hippocampal segmentation. A standard of reference from a global working group. Alzheimers Dement. 2015 Feb;11(2):107-10. doi: 10.1016/j.jalz.2014.05.1761. PMID: 25732924.

 

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Apostolova LG, Zarow C, Biado K, Hurtz S, Boccardi M, Somme J, Honarpisheh H, Blanken AE, Brook J, Tung S, Lo D, Ng D, Alger JR, Vinters HV, Bocchetta M, Duvernoy H, Jack CR Jr, Frisoni GB; EADC-ADNI Working Group on the Harmonized Protocol for Manual Hippocampal Segmentation. Relationship between hippocampal atrophy and neuropathology markers: a 7T MRI validation study of the EADC-ADNI Harmonized Hippocampal Segmentation Protocol. Alzheimers Dement. 2015 Feb;11(2):139-50. doi: 10.1016/j.jalz.2015.01.001. Epub 2015 Jan 22. PMID: 25620800; PMCID: PMC4348340.

 

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Duchesne S, Valdivia F, Robitaille N, Mouiha A, Valdivia FA, Bocchetta M, Apostolova LG, Ganzola R, Preboske G, Wolf D, Boccardi M, Jack CR Jr, Frisoni GB; EADC-ADNI Working Group on The Harmonized Protocol for Manual Hippocampal Segmentation and for the Alzheimer’s Disease Neuroimaging Initiative. Manual segmentation qualification platform for the EADC-ADNI harmonized protocol for hippocampal segmentation project. Alzheimers Dement. 2015 Feb;11(2):161-74. doi: 10.1016/j.jalz.2015.01.002. PMID: 25617509.

 

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Boccardi M, Bocchetta M, Morency FC, Collins DL, Nishikawa M, Ganzola R, Grothe MJ, Wolf D, Redolfi A, Pievani M, Antelmi L, Fellgiebel A, Matsuda H, Teipel S, Duchesne S, Jack CR Jr, Frisoni GB; EADC-ADNI Working Group on The Harmonized Protocol for Manual Hippocampal Segmentation and for the Alzheimer’s Disease Neuroimaging Initiative. Training labels for hippocampal segmentation based on the EADC-ADNI harmonized hippocampal protocol. Alzheimers Dement. 2015 Feb;11(2):175-83. doi: 10.1016/j.jalz.2014.12.002. Epub 2015 Jan 20. PMID: 25616957.

 

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Inglese P, Amoroso N, Boccardi M, Bocchetta M, Bruno S, Chincarini A, Errico R, Frisoni GB, Maglietta R, Redolfi A, Sensi F, Tangaro S, Tateo A, Bellotti R; Alzheimer’s Disease Neuroimaging Initiative. Multiple RF classifier for the hippocampus segmentation: Method and validation on EADC-ADNI Harmonized Hippocampal Protocol. Phys Med. 2015 Dec;31(8):1085-1091. doi: 10.1016/j.ejmp.2015.08.003. Epub 2015 Oct 21. PMID: 26481815.

 

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Frisoni GB, Jack CR Jr, Bocchetta M, Bauer C, Frederiksen KS, Liu Y, Preboske G, Swihart T, Blair M, Cavedo E, Grothe MJ, Lanfredi M, Martinez O, Nishikawa M, Portegies M, Stoub T, Ward C, Apostolova LG, Ganzola R, Wolf D, Barkhof F, Bartzokis G, DeCarli C, Csernansky JG, deToledo-Morrell L, Geerlings MI, Kaye J, Killiany RJ, Lehéricy S, Matsuda H, O’Brien J, Silbert LC, Scheltens P, Soininen H, Teipel S, Waldemar G, Fellgiebel A, Barnes J, Firbank M, Gerritsen L, Henneman W, Malykhin N, Pruessner JC, Wang L, Watson C, Wolf H, deLeon M, Pantel J, Ferrari C, Bosco P, Pasqualetti P, Duchesne S, Duvernoy H, Boccardi M; EADC-ADNI Working Group on The Harmonized Protocol for Manual Hippocampal Volumetry and for the Alzheimer’s Disease Neuroimaging Initiative. The EADC-ADNI Harmonized Protocol for manual hippocampal segmentation on magnetic resonance: evidence of validity. Alzheimers Dement. 2015 Feb;11(2):111-25. doi: 10.1016/j.jalz.2014.05.1756. Epub 2014 Sep 27. PMID: 25267715; PMCID: PMC4422168.

 

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Bocchetta M, Boccardi M, Ganzola R, Apostolova LG, Preboske G, Wolf D, Ferrari C, Pasqualetti P, Robitaille N, Duchesne S, Jack CR Jr, Frisoni GB; EADC-ADNI Working Group on The Harmonized Protocol for Manual Hippocampal Segmentation and for the Alzheimer’s Disease Neuroimaging Initiative. Harmonized benchmark labels of the hippocampus on magnetic resonance: the EADC-ADNI project. Alzheimers Dement. 2015 Feb;11(2):151-60.e5. doi: 10.1016/j.jalz.2013.12.019. Epub 2014 Sep 13. PMID: 25223727.

 

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Boccardi M, Bocchetta M, Ganzola R, Robitaille N, Redolfi A, Duchesne S, Jack CR Jr, Frisoni GB; EADC-ADNI Working Group on The Harmonized Protocol for Manual Hippocampal Segmentation and for the Alzheimer’s Disease Neuroimaging Initiative. Operationalizing protocol differences for EADC-ADNI manual hippocampal segmentation. Alzheimers Dement. 2015 Feb;11(2):184-94. doi: 10.1016/j.jalz.2013.03.001. Epub 2013 May 21. PMID: 23706515.

 

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Morbelli S, Brugnolo A, Bossert I, Buschiazzo A, Frisoni GB, Galluzzi S, van Berckel BN, Ossenkoppele R, Perneczky R, Drzezga A, Didic M, Guedj E, Sambuceti G, Bottoni G, Arnaldi D, Picco A, De Carli F, Pagani M, Nobili F. Visual versus semi-quantitative analysis of 18F-FDG-PET in amnestic MCI: an European Alzheimer’s Disease Consortium (EADC) project. J Alzheimers Dis. 2015;44(3):815-26. doi: 10.3233/JAD-142229. PMID: 25362041.

 

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Pagani M, De Carli F, Morbelli S, Öberg J, Chincarini A, Frisoni GB, Galluzzi S, Perneczky R, Drzezga A, van Berckel BN, Ossenkoppele R, Didic M, Guedj E, Brugnolo A, Picco A, Arnaldi D, Ferrara M, Buschiazzo A, Sambuceti G, Nobili F. Volume of interest-based [18F]fluorodeoxyglucose PET discriminates MCI converting to Alzheimer’s disease from healthy controls. A European Alzheimer’s Disease Consortium (EADC) study. Neuroimage Clin. 2014 Nov 18;7:34-42. doi: 10.1016/j.nicl.2014.11.007. PMID: 25610765; PMCID: PMC4299956.

 

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Perani D, Della Rosa PA, Cerami C, Gallivanone F, Fallanca F, Vanoli EG, Panzacchi A, Nobili F, Pappatà S, Marcone A, Garibotto V, Castiglioni I, Magnani G, Cappa SF, Gianolli L; EADC-PET Consortium. Validation of an optimized SPM procedure for FDG-PET in dementia diagnosis in a clinical setting. Neuroimage Clin. 2014 Oct 24;6:445-54. doi: 10.1016/j.nicl.2014.10.009. PMID: 25389519; PMCID: PMC4225527.

 

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Bocchetta M, Galluzzi S, Kehoe PG, Aguera E, Bernabei R, Bullock R, Ceccaldi M, Dartigues JF, de Mendonça A, Didic M, Eriksdotter M, Félician O, Frölich L, Gertz HJ, Hallikainen M, Hasselbalch SG, Hausner L, Heuser I, Jessen F, Jones RW, Kurz A, Lawlor B, Lleo A, Martinez-Lage P, Mecocci P, Mehrabian S, Monsch A, Nobili F, Nordberg A, Rikkert MO, Orgogozo JM, Pasquier F, Peters O, Salmon E, Sánchez-Castellano C, Santana I, Sarazin M, Traykov L, Tsolaki M, Visser PJ, Wallin ÅK, Wilcock G, Wilkinson D, Wolf H, Yener G, Zekry D, Frisoni GB. The use of biomarkers for the etiologic diagnosis of MCI in Europe: an EADC survey. Alzheimers Dement. 2015 Feb;11(2):195-206.e1. doi: 10.1016/j.jalz.2014.06.006. Epub 2014 Aug 20. PMID: 25150733.

 

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Bocchetta M, Galluzzi S, Kehoe PG, Aguera E, Bernabei R, Bullock R, Ceccaldi M, Dartigues JF, de Mendonça A, Didic M, Eriksdotter M, Félician O, Frölich L,
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Boccardi M, Bocchetta M, Apostolova LG, Barnes J, Bartzokis G, Corbetta G, DeCarli C, deToledo-Morrell L, Firbank M, Ganzola R, Gerritsen L, Henneman W, Killiany RJ, Malykhin N, Pasqualetti P, Pruessner JC, Redolfi A, Robitaille N, Soininen H, Tolomeo D, Wang L, Watson C, Wolf H, Duvernoy H, Duchesne S, Jack CR Jr, Frisoni GB; EADC-ADNI Working Group on the Harmonized Protocol for Manual Hippocampal Segmentation. Delphi definition of the EADC-ADNI Harmonized Protocol for hippocampal segmentation on magnetic resonance. Alzheimers Dement. 2015 Feb;11(2):126-38. doi: 10.1016/j.jalz.2014.02.009. Epub 2014 Aug 15. PMID: 25130658; PMCID: PMC4419736.

 

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Della Rosa PA, Cerami C, Gallivanone F, Prestia A, Caroli A, Castiglioni I, Gilardi MC, Frisoni G, Friston K, Ashburner J, Perani D; EADC-PET Consortium. A standardized [18F]-FDG-PET template for spatial normalization in statistical parametric mapping of dementia. Neuroinformatics. 2014 Oct;12(4):575-93. doi: 10.1007/s12021-014-9235-4. PMID: 24952892.

 

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Boccardi M, Bocchetta M, Apostolova LG, Preboske G, Robitaille N, Pasqualetti P, Collins LD, Duchesne S, Jack CR Jr, Frisoni GB; EADC-ADNI Working Group on The Harmonized Protocol for Hippocampal Volumetry; Alzheimer’s Disease Neuroimaging Initiative. Establishing magnetic resonance images orientation for the EADC-ADNI manual hippocampal segmentation protocol. J Neuroimaging. 2014 Sep-Oct;24(5):509-14. doi: 10.1111/jon.12065. Epub 2013 Nov 26. PMID: 24279479.

 

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Morbelli S, Drzezga A, Perneczky R, Frisoni GB, Caroli A, van Berckel BN, Ossenkoppele R, Guedj E, Didic M, Brugnolo A, Sambuceti G, Pagani M, Salmon E, Nobili F. Resting metabolic connectivity in prodromal Alzheimer’s disease. A European Alzheimer Disease Consortium (EADC) project. Neurobiol Aging. 2012 Nov;33(11):2533-50. doi: 10.1016/j.neurobiolaging.2012.01.005. Epub 2012 Feb 23. PMID: 22365486.

 

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Caroli A, Prestia A, Chen K, Ayutyanont N, Landau SM, Madison CM, Haense C, Herholz K, Nobili F, Reiman EM, Jagust WJ, Frisoni GB; EADC-PET Consortium, NEST-DD, and Alzheimer’s Disease Neuroimaging Initiative. Summary metrics to assess Alzheimer disease-related hypometabolic pattern with 18F-FDG PET: head- to-head comparison. J Nucl Med. 2012 Apr;53(4):592-600. doi: 10.2967/jnumed.111.094946. Epub 2012 Feb 17. PMID: 22343502; PMCID: PMC3640308.

 

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Boccardi M, Bocchetta M, Morency FC, Collins DL, Nishikawa M, Ganzola R, Grothe MJ, Wolf D, Redolfi A, Pievani M, Antelmi L, Fellgiebel A, Matsuda H, Teipel S, Duchesne S, Jack CR Jr, Frisoni GB; EADC-ADNI Working Group on The Harmonized Protocol for Manual Hippocampal Segmentation and for the Alzheimer’s Disease Neuroimaging Initiative. Training labels for hippocampal segmentation based on the EADC-ADNI harmonized hippocampal protocol. Alzheimers Dement. 2015 Feb;11(2):175-83. doi: 10.1016/j.jalz.2014.12.002. Epub 2015 Jan 20. PMID: 25616957.

 

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Boccardi M, Ganzola R, Bocchetta M, Pievani M, Redolfi A, Bartzokis G, Camicioli R, Csernansky JG, de Leon MJ, deToledo-Morrell L, Killiany RJ, Lehéricy S, Pantel J, Pruessner JC, Soininen H, Watson C, Duchesne S, Jack CR Jr, Frisoni GB. Survey of protocols for the manual segmentation of the hippocampus: preparatory steps towards a joint EADC-ADNI harmonized protocol. J Alzheimers Dis. 2011;26 Suppl 3(0 3):61-75. doi: 10.3233/JAD-2011-0004. Erratum in: J Alzheimers Dis. 2012 Jan 1;30(2):461. PMID: 21971451; PMCID: PMC3829626.

 

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Tsolaki M, Papaliagkas V, Anogianakis G, Bernabei R, Emre M, Frolich L, Visser PJ, Michel JP, Pirttila T, Olde Rikkert M, Soininen H, Sobow T, Vellas B, Verhey F, Winblad B; European Alzheimer Disease Consortium. Consensus statement on dementia education and training in Europe. J Nutr Health Aging. 2010 Feb;14(2):131-5. doi: 10.1007/s12603-009-0238-z. PMID: 20126961.

 

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Slats D, Spies PE, Sjögren MJ, Visser PJ, Verbeek MM, Rikkert MG, Kehoe PG. CSF biomarker utilisation and ethical considerations of biomarker assisted diagnosis and research in dementia: perspectives from within the European Alzheimer’s Disease Consortium (EADC). J Neurol Neurosurg Psychiatry. 2010 Jan;81(1):124-5. doi: 10.1136/jnnp.2009.176412. PMID: 20019235.

 

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Winblad B, Frisoni GB, Frolich L, Johannsen P, Johansson G, Kehoe P, Lovestone S, Olde-Rikkert M, Reynish E, Visser PJ, Vellas B. Editorial: EADC (European Alzheimer Disease Consortium) recommendations for future Alzheimer disease research in Europe. J Nutr Health Aging. 2008 Dec;12(10):683-4. doi: 10.1007/BF03028614. PMID: 19043641.

 

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Frisoni GB, Henneman WJ, Weiner MW, Scheltens P, Vellas B, Reynish E, Hudecova J, Hampel H, Burger K, Blennow K, Waldemar G, Johannsen P, Wahlund LO, Zito G, Rossini PM, Winblad B, Barkhof F; Alzheimer’s Disease Neuroimaging Initiative. The pilot European Alzheimer’s Disease Neuroimaging Initiative of the European Alzheimer’s Disease Consortium. Alzheimers Dement. 2008 Jul;4(4):255-64. doi: 10.1016/j.jalz.2008.04.009. PMID: 18631976; PMCID: PMC2657833.

 

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Petrovic M, Hurt C, Collins D, Burns A, Camus V, Liperoti R, Marriott A, Nobili F, Robert P, Tsolaki M, Vellas B, Verhey F, Byrne EJ. Clustering of behavioural and psychological symptoms in dementia (BPSD): a European Alzheimer’s disease consortium (EADC) study. Acta Clin Belg. 2007 Nov- Dec;62(6):426-32. doi: 10.1179/acb.2007.062. PMID: 18351187.

 

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Vellas B; European Alzheimer’s Disease Consortium. Editorial: disease modifying trials in Alzheimer’s disease: an EADC (European Alzheimer’s Disease Consortium) initiative. J Nutr Health Aging. 2006 Mar-Apr;10(2):112. PMID: 16554942.

 

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Portet F, Ousset PJ, Visser PJ, Frisoni GB, Nobili F, Scheltens P, Vellas B, Touchon J; MCI Working Group of the European Consortium on Alzheimer’s Disease (EADC). Mild cognitive impairment (MCI) in medical practice: a critical review of the concept and new diagnostic procedure. Report of the MCI Working Group of the European Consortium on Alzheimer’s Disease. J Neurol Neurosurg Psychiatry. 2006 Jun;77(6):714-8. doi: 10.1136/jnnp.2005.085332. Epub 2006 Mar 20. PMID: 16549412; PMCID: PMC2077456.

 

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Paulino Ramirez Diaz S, Gil Gregório P, Manuel Ribera Casado J, Reynish E, Jean Ousset P, Vellas B, Salmon E. The need for a consensus in the use of assessment tools for Alzheimer’s disease: the Feasibility Study (assessment tools for dementia in Alzheimer Centres across Europe), a European Alzheimer’s Disease onsortium’s (EADC) survey. Int J Geriatr Psychiatry. 2005 Aug;20(8):744-8. doi: 10.1002/gps.1355. PMID: 16035121.

 

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Frisoni GB, Scheltens Ph, Galluzzi S, Nobili FM, Fox NC, Robert PH, Soininen H, Wahlund LO, Waldemar G, Salmon E. Neuroimaging tools to rate regional atrophy, subcortical cerebrovascular disease, and regional cerebral blood flow and metabolism: consensus paper of the EADC. J Neurol Neurosurg Psychiatry. 2003 Oct;74(10):1371-81. doi: 10.1136/jnnp.74.10.1371. PMID: 14570828; PMCID: PMC1757396.

 

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